Arquivos de Asma, Alergia e Imunologia
http://www.aaai.periodikos.com.br/article/doi/10.5935/2526-5393.20250008
Arquivos de Asma, Alergia e Imunologia
Special Article

Reações de hipersensibilidade a vacinas e imunização de pacientes com asma: recomendações conjuntas da Associação Brasileira de Alergia e Imunologia e da Sociedade Brasileira de Imunizações

Hypersensitivity reactions to vaccines and immunization in patients with asthma: joint recommendations of the Brazilian Association of Allergy and Immunology and the Brazilian Immunization Society

Ana Karolina Barreto Berselli Marinho; Claudia França Cavalcante Valente; Ekaterini Simões Goudoris; Anete Sevciovic Grumach; Fátima Rodrigues Fernandes; Claudia Leiko Yonekura Anagusko; Clarissa Morais Busatto Gerhardt; Gisele Feitosa Zuvanov Casado; Angelica Varela Rondon; Monica Araujo Álvares Silva; Ronney Corrêa Mendes; Antonio Paulo Costa Penido; Lorena de Castro Diniz; Bianca Noleto Ayres Guimarães; Ana Paula Neves Burian; Renato de Ávila Kfouri; Mônica Levi; Fabio Chigres Kuschnir

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Resumo

Este artigo oferece informações e recomendações sobre reações de hipersensibilidade a vacinas e imunização de pacientes com asma. Apresenta-se uma análise das reações de hipersensibilidade imediata e tardia às vacinas, enfatizando a importância da avaliação cuidadosa dos antecedentes alérgicos do paciente e do uso de testes diagnósticos específicos para identificar sensibilizações. Discute-se ainda a aplicação de estratégias como a vacinação em doses fracionadas, visando minimizar o risco de reações alérgicas graves. O artigo também explora a segurança e a eficácia de vacinas recentes, como as para dengue, COVID-19, vírus sincicial respiratório recombinante e doenças pneumocócicas no contexto dos pacientes alérgicos, incluindo aqueles com asma. A imunização segura desse grupo de pacientes é essencial não apenas para a proteção individual, mas também para a saúde coletiva, prevenindo surtos de doenças infecciosas e aumentando a confiança nas campanhas de vacinação. As recomendações apresentadas nesta publicação foram adaptadas ao contexto brasileiro e ajustadas por consenso entre especialistas membros da Associação Brasileira de Alergia e Imunologia (ASBAI) e da Sociedade Brasileira de Imunizações (SBIm).

Palavras-chave

Alergia; asma; hipersensibilidade; imunidade; vacinas.

Abstract

This article provides information and recommendations on hypersensitivity reactions to vaccines and the immunization of patients with asthma. We present an analysis of both immediate and delayed reactions, emphasizing the importance of a thorough assessment of the patient's allergy history and the use of specific diagnostic tests to identify sensitizations. We also discuss strategies such as fractional dose vaccination, with the goal of minimizing the risk of severe allergic reactions. Finally, we explore the safety and effectiveness of new vaccines, including those for dengue infection, COVID-19, respiratory syncytial virus, and pneumococcal diseases, in the setting of hypersensitivity reactions and/or immunization of patients with asthma. Ensuring safe immunization for this group of patients is essential not only for individual protection but also for public health, by preventing outbreaks of infectious diseases and increasing confidence in vaccination programs.The recommendations presented here were adapted to the Brazilian context and developed by consensus among allergy and immunology experts from the Brazilian Association of Allergy and Immunology (ASBAI) and the Brazilian Immunization Society (SBIm).

Keywords

Allergy; asthma; hypersensitivity; immunity; vaccines.

References

1. Shattock AJ, Johnson HC, Sim SY, Carter A, Lambach P, Hutubessy RCW, et al. Contribution of vaccination to improved survival and health: modelling 50 years of the Expanded Programme on Immunization. Lancet. 2024 May 25;403(10441):2307-16. doi: 10.1016/S0140-6736(24)00850-X.

2. Lötvall J, Pawankar R, Wallace DV, Akdis CA, Rosenwasser LJ, Weber RW, et al. ; American Academy of Allergy, Asthma & Immunology (AAAAI); American College of Allergy, Asthma & Immunology (ACAAI); European Academy of Allergy and Clinical Immunology (EAACI); World Allergy Organization (WAO). We call for iCAALL: International Collaboration for Asthma, Allergy and Immunology. Ann Allergy Asthma Immunol.2012 Apr;108(4):215-6.doi:10.1016/j. anai.2012.02.025.

3. Johansson SG, Bieber T, Dahl R, Friedmann PS, Lanier BQ, Lockey RF, et al.Revised nomenclature for allergy for global use:Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003.J Allergy Clin Immunol. 2004 May;113(5):832-6.doi: 10.1016/j.jaci.2003.12.591.

4. Mahler V, Junker AC. Anaphylaxis to additives in vaccines. Allergo J Int. 2022;31(5):123-36. doi:10.1007/s40629-022-00215-8.

5. Demoly P, Adkinson NF, Brockow K, Castells M, Chiriac AM, Greenberger PA, et al. International Consensus on drug allergy. Allergy. 2014 Apr;69(4):420-37. doi: 10.1111/all.12350.

6. Clarkson TW, Magos L, Myers GJ. The toxicology of mercury-current exposures and clinical manifestations. N Engl J Med. 2003;349(18):1731-7. doi:10.1056/NEJMra022471.

7. Cardona V, Ansotegui IJ, Ebisawa M, El-Gamal Y, Fernandez Rivas M, Fineman S, et al. World allergy organization anaphylaxis guidance 2020.World Allergy Organ J.2020 Oct 30;13(10):100472. doi: 10.1016/j.waojou.2020.100472.

8. Bohlke K, Davis RL, Marcy SM, Braun MM, DeStefano F, Black SB, et al. ; Vaccine Safety Datalink Team. Risk of anaphylaxis after vaccination of children and adolescents. Pediatrics. 2003 Oct;112(4):815-20. doi: 10.1542/peds.112.4.815.

9. McNeil MM, Weintraub ES, Duffy J, Sukumaran L, Jacobsen SJ, Klein NP, et al. Risk of anaphylaxis after vaccination in children and adults. J Allergy Clin Immunol. 2016 Mar;137(3):868-78. doi: 10.1016/j.jaci.2015.07.048.

10. Su JR, Moro PL, Ng CS, Lewis PW, Said MA, Cano MV.Anaphylaxis after vaccination reported to the Vaccine Adverse Event Reporting System, 1990-2016. J Allergy Clin Immunol. 2019;143(4):1465-73. doi:10.1016/j.jaci.2018.12.1003.

11. Choe YJ, Lee H, Kim JH, Choi WS, Shin JY. Anaphylaxis following vaccination among children in Asia: A large-linked database study. Allergy. 2021;76(4):1246-9. doi:10.1111/all.14562.

12. Kelso JM, Greenhawt MJ, Li JT, Nicklas RA, Bernstein DI, Blessing-Moore J, et al. Adverse reactions to vaccines practice parameter 2012 update. J Allergy Clin Immunol. 2012 Jul;130(1):25-43. doi: 10.1016/j.jaci.2012.04.003.

13. Taylor S, Asmundson GJG.Immunization stress-related responses: implications for vaccination hesitancy and vaccination processes during the COVID-19 pandemic.J Anxiety Disord.2021;84:102489. doi:10.1016/j.janxdis.2021.102489.

14. Gold MS, MacDonald NE, McMurtry CM, Balakrishnan MR, HeiningerU,Menning L,et al.Immunizationstress-relatedresponse-Redefining immunization anxiety-related reaction as an adverse event following immunization. Vaccine. 2020 Mar 23;38(14):30153020. doi: 10.1016/j.vaccine.2020.02.046.

15. Pérez Rubio A, Eiros JM. Cell culture-derived flu vaccine: Present and future. Human Vaccines & Immunotherapeutics. 2018;14(8): 1874-82. doi: 10.1080/21645515.2018.1460297.

16. McNeil MM, DeStefano F. Vaccine-associated hypersensitivity. J Allergy Clin Immunol. 2018;141(2):463-72. doi:10.1016/j. jaci.2017.12.971.

17. Dreskin SC, Halsey NA, Kelso JM, Wood RA, Hummell DS, Edwards KM, et al. International Consensus (ICON): allergic reactions to vaccines.World Allergy Organ J.2016 Sep 16;9(1):32.doi:10.1186/s40413-016-0120-5.

18. James JM, Burks AW, Roberson PK, Sampson HA. Safe administration of the measles vaccine to children allergic to eggs. N Engl J Med. 1995;332(19):1262-6. doi:10.1056/NEJM199505113321904.

19. Baxter DN. Measles immunization in children with a history of egg allergy. Vaccine. 1996;14(2):131-4. doi:10.1016/0264410x(95)00154-s.

20. Kelso JM. Influenza vaccine and egg allergy: nearing the end of an evidence-based journey. J Allergy Clin Immunol Pract. 2015;3(1):140-1. doi:10.1016/j.jaip.2014.08.011.

21. Kelso JM. Administering influenza vaccine to egg-allergic persons. Expert Rev Vaccines.2014;13(8):1049-57.doi:10.1586/14760584. 2014.933079.

22. Takey PRG.Imunogenicidade e segurança da vacina contra a febre amarela:revisão sistemática e metanálise [tese].Rio de Janeiro, RJ: Fundação Oswaldo Cruz, Instituto Nacional de Infectologia Evandro Chagas (INI) -Programa de Pós-graduação em Pesquisa Clínica em DoençasInfecciosas;2020.Disponível em:https://sucupiralegado.capes.gov.br/sucupira/public/consultas/coleta/trabalho Conclusao/viewTrabalhoConclusao.jsf?popup=true&id_trabalho=10263752 .

23. Gerhardt CMB, Feitosa GSJ, Aquilante BP, Dorna MB, Santos CJN, Pastorino AC, et al. Segurança da vacina de febre amarela em pacientes comprovadamente alérgicos à proteína do ovo. Arq Asma Alerg Imunol. 2019;3(2):143-50. doi: 10.5935/25265393.20190025.

24. Gerhardt CMB, Castro APBM, Pastorino AC, Dorna MB, Nunes-Santos CJ, Aquilante BP, et al. Safety of yellow fever vaccine administration in confirmed egg-allergic patients. Vaccine. 2020 Sep 29;38(42):6539-44. doi: 10.1016/j.vaccine.2020.08.020.

25. Cancado B, Aranda C, Mallozi M, Weckx L, Sole D. Yellow fever vaccine and egg allergy. Lancet Infect Dis. 2019;19(8):812. doi:10.1016/S1473-3099(19)30355-X.

26. Guimarães BNA, Petraglia TCMB, Marinho AKBB, Barbosa ADM. Eventos adversos imediatos à vacina febre amarela em crianças alérgicas ao ovo. Arq Asma Alerg Imunol. 2022;6(4):519-26. doi: 10.5935/2526-5393.20220060.

27. Kattan JD, Konstantinou GN, Cox AL, Nowak-Wegrzyn A, Gimenez G, SampsonHA,etal.Anaphylaxis todiphtheria, tetanus,andpertussis vaccines among children with cow's milk allergy. J Allergy Clin Immunol. 2011 Jul;128(1):215-8. doi: 10.1016/j.jaci.2011.04.046.

28. SBIm, ASBAI, SBP. Nota técnica conjunta SBIm/ASBAI/SBP - 08/02/2017.Vacina rotavírus [Internet].Disponível em:https://sbim.org.br/images/files/nota-sbim-asbai-sbp-rotavirus08022017-v2.pdf. Acessado em: 01/11/2024.

29. Kumagai T, Yamanaka T, Wataya Y, Umetsu A, Kawamura N, Ikeda K, et al. Gelatin-specific humoral and cellular immune responses in children with immediate- and nonimmediate-type reactions to live measles, mumps, rubella, and varicella vaccines. J Allergy Clin Immunol.1997 Jul;100(1):130-4.doi:10.1016/s00916749(97)70204-5.

30. Pool V, Braun MM, Kelso JM, Mootrey G, Chen RT, Yunginger JW, et al. ;VAERS Team.US Vaccine Adverse Event Reporting System. Prevalence of anti-gelatin IgE antibodies in people with anaphylaxis after measles-mumps rubella vaccine in the United States.Pediatrics. 2002 Dec;110(6):e71. doi: 10.1542/peds.110.6.e71.

31. Russell M, Pool V, Kelso JM, Tomazic-Jezic VJ.Vaccination of persons allergic to latex: a review of safety data in the Vaccine Adverse Event Reporting System (VAERS). Vaccine. 2004;23(5):664-7. doi:10.1016/j.vaccine.2004.06.042.

32. Nicaise-Roland P, Granger V, Soria A, Barbaud A, Pallardy M, Chollet-Martin S, et al. Immediate hypersensitivity to COVID-19 vaccines: Focus on biological diagnosis. Front Allergy. 2022 Sep 30;3:1007602. doi: 10.3389/falgy.2022.1007602.

33. Wenande E, Garvey LH. Immediate-type hypersensitivity to polyethylene glycols:a review.Clin Exp Allergy.2016 Jul;46(7):907-22. doi: 10.1111/cea.12760.

34. Loughlin AM, Marchant CD, Adams W, Barnett E, Baxter R, Black S, et al. Causality assessment of adverse events reported to the Vaccine Adverse Event Reporting System (VAERS).Vaccine.2012 Nov 26;30(50):7253-9. doi: 10.1016/j.vaccine.2012.09.074.

35. National Center for Immunization and Respiratory Diseases.General recommendations on immunization - Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR. 2011;60(2):1-64.

36. Ma L, Du X, Dong Y, Peng L, Han X, Lyu J, et al. First case of Stevens-Johnson syndrome after rabies vaccination. Br J Clin Pharmacol. 2018 Apr;84(4):803-5. doi: 10.1111/bcp.13512.

37. Christou EM, Wargon O. Stevens-Johnson syndrome after varicella vaccination. Med J Aust. 2012;196(4):240-1. doi:10.5694/ mja11.11484.

38. Chahal D, Aleshin M, Turegano M, Chiu M, Worswick S. Vaccine-induced toxic epidermal necrolysis: a case and systematic review. Dermatol Online J. 2018;24(1). doi:10.5070/D3241037941.

39. Keller N, Gilad O, Marom D, Marcus N, Garty BZ. Nonbullous Erythema Multiforme in Hospitalized Children: A 10-Year Survey. Pediatr Dermatol. 2015;32(5):701-3. doi:10.1111/pde.12659.

40. Canavan TN, Mathes EF, Frieden I, Shinkai K. Mycoplasma pneumoniae-induced rash and mucositis as a syndrome distinct from Stevens-Johnson syndrome and erythema multiforme:a systematic review. J Am Acad Dermatol. 2015;72(2):239-45. doi:10.1016/j. jaad.2014.06.026.

41. Stone Jr CA, Rukasin CRF, Beachkofsky TM, Phillips EJ. Immune-mediated adverse reactions to vaccines. Br J Clin Pharmacol. 2019;85(12):2694-706. doi:10.1111/bcp.14112.

42. Phillips EJ, Bigliardi P, Bircher AJ, Broyles A, Chang YS, Chung WH, et al. Controversies in drug allergy: Testing for delayed reactions. J Allergy Clin Immunol. 2019 Jan;143(1):66-73. doi: 10.1016/j. jaci.2018.10.030.

43. Peng B, Wei M, Zhu FC, Li JX. The vaccines-associated Arthus reaction. Hum Vaccines Immunother. 2019;15(11):2769-77. doi:1 0.1080/21645515.2019.1602435.

44. Pool V, Mege L, Abou-Ali A. Arthus Reaction as an Adverse Event Following Tdap Vaccination.Vaccines.2020;8(3):385. doi:10.3390/ vaccines8030385.

45. Willison HJ, Jacobs BC, Doorn PA van. Guillain-Barré syndrome. The Lancet. 2016;388(10045):717-27. doi:10.1016/S01406736(16)00339-1.

46. Brasil, Ministério da Saúde. Painel de Monitoramento das Arboviroses [Internet]. Disponível em: https://www.gov.br/saude/ pt-br/assuntos/saude-de-a-a-z/a/aedes-aegypti/monitoramentodas-arboviroses/painel . Acessado em: 28/08/2024.

47. Yang F, Schildhauer S, Billeter SA, Hardstone Yoshimizu M, Payne R, Pakingan MJ, et al. Insecticide Resistance Status of Aedes aegypti (Diptera: Culicidae) in California by Biochemical Assays. J Med Entomol. 2020 Jul 4;57(4):1176-83. doi: 10.1093/jme/tjaa031.

48. Barcellos C, Matos V, Lana RM, Lowe R. Climate change, thermal anomalies, and the recent progression of dengue in Brazil.Sci Rep. 2024;14(1):5948. doi:10.1038/s41598-024-56044-y

49. Tricou V, Yu D, Reynales H, Biswal S, Saez-Llorens X, Sirivichayakul C, et al. Long-term efficacy and safety of a tetravalent dengue vaccine (TAK-003): 4·5-year results from a phase 3, randomised, double-blind, placebo-controlled trial. Lancet Glob Health. 2024 Feb;12(2):e257-e270. doi: 10.1016/S2214-109X(23)00522-3.

50. Patel SS, Rauscher M, Kudela M, Pang H.Clinical safety experience of TAK-003 for dengue fever:a new tetravalent live attenuated vaccine candidate. Clin Infect Dis. 2023;76(3):e1350-e1359. doi:10.1093/ cid/ciac418.

51. Anvisa - Agência Nacional de Vigilância Sanitária. Segurança da vacina Qdenga [Internet].Disponível em:https://www.gov.br/anvisa/pt-br/assuntos/noticias-anvisa/seguranca-da-vacina-qdenga . Acessado em: 29/08/2024.

52. Percio J, Kobayashi CD, Silva RMA, Marinho AKBB, Capovilla L, Andrade PHS, et al. Safety signal detected: Anaphylaxis after attenuated dengue vaccine (TAK-003) -Brazil, march 1, 2023march 11, 2024.Vaccine.2024 Dec 2;42(26):126407.doi:10.1016/j. vaccine.2024.126407.

53. Brasil, Ministério da Saúde.Nota Técnica N° 7/2024-CGFAM/DPNI/ SVSA/MS [Internet]. Disponível em: https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/notas-tecnicas/2024/nota-tecnica-no-7-2024-cgfam-dpni-svsa-ms/view .Acessado em: 29/08/2024.

54. Krantz MS, Liu Y, Phillips EJ, Stone CA. COVID-19 vaccine anaphylaxis: PEG or not? Allergy. 2021;76(6):1934-7. doi:10.1111/ all.14722.

55. Guerrini G, Gioria S, Sauer AV, Lucchesi S, Montagnani F, Pastore G, et al.Monitoring Anti-PEG Antibodies Level upon Repeated Lipid Nanoparticle-Based COVID-19 Vaccine Administration. Int J Mol Sci. 2022 Aug 9;23(16):8838. doi: 10.3390/ijms23168838.

56. Lukawska J, Mandaliya D, Chan AWE, Foggitt A, Bidder T, Harvey J, et al. Anaphylaxis to trometamol excipient in gadolinium-based contrast agents for clinical imaging. J Allergy Clin Immunol Pract. 2019 Mar;7(3):1086-7. doi: 10.1016/j.jaip.2018.08.035.

57. Guler S, Ertok I, Sahin NY, Ramadan H, Katirci Y.Anaphylaxis after intravenous infusion of dexketoprofen trometamol. Turk J Emerg Med. 2016;16(3):132-3. doi:10.1016/j.tjem.2016.09.003.

58. Maltezou HC, Anastassopoulou C, Hatziantoniou S, Poland GA, Tsakris A.Anaphylaxis rates associated with COVID-19 vaccines are comparable to those of other vaccines.Vaccine.2022;40(2):183-6. doi:10.1016/j.vaccine.2021.11.066.

59. Boufidou F, Hatziantoniou S, Theodoridou K, Maltezou HC, Vasileiou K, Anastassopoulou C, et al. Anaphylactic Reactions to COVID-19 Vaccines: An Updated Assessment Based on Pharmacovigilance Data. Vaccines (Basel). 2023 Mar 8;11(3):613. doi: 10.3390/ vaccines11030613.

60. Baeck M, Marot L, Belkhir L. Delayed large local reactions to mRNA vaccines. N Engl J Med. 2021;384(24):e98. doi:10.1056/ NEJMc2104751.

61. Blumenthal KG, Freeman EE, Saff RR, Robinson LB, Wolfson AR, Foreman RK, et al. Delayed Large Local Reactions to mRNA1273 Vaccine against SARS-CoV-2. N Engl J Med. 2021 Apr 1;384(13):1273-7. doi: 10.1056/NEJMc2102131.

62. Samarakoon U, Alvarez-Arango S, Blumenthal KG. Delayed Large Local Reactions to mRNA Covid-19 Vaccines in Blacks, Indigenous Persons, and People of Color. N Engl J Med. 2021 Aug 12;385(7):662-4. doi: 10.1056/NEJMc2108620.

63. Higashino T, Yamazaki Y, Senda S, Satou Y, Yonekura Y, Imai K, et al. Assessment of Delayed Large Local Reactions After the First Dose of the SARS-CoV-2 mRNA-1273 Vaccine in Japan.JAMA Dermatol. 2022 Aug 1;158(8):923-7. doi: 10.1001/jamadermatol.2022.2088.

64. Baden LR, El Sahly HM, Essink B, Kotloff K, Frey S, Novak R, et al. ; COVE Study Group. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N Engl J Med. 2021 Feb 4;384(5):403-16. doi: 10.1056/NEJMoa2035389.

65. Global Initiative for Asthma.2024 Global Initiative for Asthma (GINA) report: global strategy for asthma management and prevention [Internet]. Disponível em: https://ginasthma.org/wp-content/uploads/2024/05/GINA-2024-Strategy-Report-24_05_22_WMS. pdf. Acessado em: 29/08/2024.

66. Brasil, Ministério da Saúde. Em 2021, SUS registrou 1,3 milhão de atendimentos a pacientes com asma na Atenção Primária à Saúde [Internet]. Disponível em: https://www.gov.br/saude/pt-br/assuntos/noticias/2022/maio/em-2021-sus-registrou-1-3-milhaode-atendimentos-a-pacientes-com-asma-na-atencao-primaria-asaude-1 . Acessado em: 26/08/2024.

67. Marques CPC, Bloise RF, Lopes LBM, Godói LF, Souza PRP, Santa Rosa IM, et al. Epidemiologia da asma no Brasil, no período de 2016 a 2020.Res Soc Dev.2022;11(8):e5211828825-e5211828825. doi:10.33448/rsd-v11i8.28825.

68. Ritchie AI, Jackson DJ, Edwards MR, Johnston SL.Airway epithelial orchestrationofinnate immunefunction inresponse to virusinfection. A focus on asthma. Ann Am Thorac Soc. 2016;13 Suppl 1:S55-63. doi:10.1513/AnnalsATS.201507-421MG.

69. Gill MA, Bajwa G, George TA, Dong CC, Dougherty II, Jiang N, et al. Counterregulation between the FcepsilonRI pathway and antiviral responses in human plasmacytoid dendritic cells. J Immunol. 2010 Jun 1;184(11):5999-6006. doi: 10.4049/jimmunol.0901194.

70. PapadopoulosNG,ChristodoulouI,RohdeG,AgacheI,AlmqvistC, Bruno A, et al.Viruses and bacteria in acute asthma exacerbations- a GA² LEN-DARE systematic review.Allergy.2011 Apr;66(4):458-68. doi: 10.1111/j.1398-9995.2010.02505.x.

71. Wark PAB. Why are people with asthma more susceptible to influenza? Eur Respir J.2019;54(4).doi:10.1183/13993003.017482019.

72. Vasileiou E, Sheikh A, Butler CC, Robertson C, Kavanagh K, Englishby T, et al. Seasonal Influenza Vaccine Effectiveness in People With Asthma:A National Test-Negative Design Case-Control Study. Clin Infect Dis. 2020 Oct 23;71(7):e94-e104. doi: 10.1093/ cid/ciz1086.

73. DiazGranados CA, Dunning AJ, Kimmel M, Kirby D, Treanor J, Collins A, et al.Efficacy of high-dose versus standard-dose influenza vaccine in older adults. N Engl J Med. 2014 Aug 14;371(7):635-45. doi: 10.1056/NEJMoa1315727.

74. Chang LJ, Meng Y, Janosczyk H, Landolfi V, Talbot HK, QHD00013 Study Group.Safety and immunogenicity of high-dose quadrivalent influenza vaccine in adults ≥65 years of age:A phase 3 randomized clinical trial. Vaccine. 2019;37(39):5825-34. doi:10.1016/j. vaccine.2019.08.016

75. U.S. Food and Drug Administration (FDA). 2020. Package Insert- Fluzone High-Dose Quadrivalent. Sanofi Pasteur [Internet]. Disponível em: www.fda.gov/media/132238/download. Acessado em: 26/08/2024.

76. Li Y, Wang X, Blau DM, Caballero MT, Feikin DR, Gill CJ, et al. ; Respiratory Virus Global Epidemiology Network; Nair H; RESCEU investigators. Global, regional, and national disease burden estimates of acute lower respiratory infections due to respiratory syncytial virus in children younger than 5 years in 2019:a systematic analysis. Lancet. 2022 May 28;399(10340):2047-64. doi: 10.1016/ S0140-6736(22)00478-0.

77. Shi T, Vennard S, Jasiewicz F, Brogden R, Nair H; RESCEU Investigators. Disease Burden Estimates of Respiratory Syncytial Virus related Acute Respiratory Infections in Adults With Comorbidity: A Systematic Review and Meta-Analysis. J Infect Dis. 2022 Aug 12;226(Suppl 1):S17-S21. doi: 10.1093/infdis/jiab040.

78. Zhou H, Thompson WW, Viboud CG, Ringholz CM, Cheng PY, Steiner C, et al. Hospitalizations associated with influenza and respiratory syncytial virus in the United States, 1993-2008. Clin Infect Dis. 2012 May;54(10):1427-36. doi: 10.1093/cid/cis211.

79. Binns E, Tuckerman J, Licciardi PV, Wurzel D. Respiratory syncytial virus, recurrent wheeze and asthma: A narrative review of pathophysiology, prevention and future directions. J Paediatr Child Health. 2022;58(10):1741-6. doi:10.1111/jpc.16197.

80. Rosas-Salazar C, Chirkova T, Gebretsadik T, Chappell JD, Peebles RS Jr, Dupont WD, et al.Respiratory syncytial virus infection during infancy and asthma during childhood in the USA (INSPIRE): a population-based, prospective birth cohort study.Lancet.2023 May 20;401(10389):1669-80. doi: 10.1016/S0140-6736(23)00811-5.

81. Coutts J, Fullarton J, Morris C, Grubb E, Buchan S, Rodgers-Gray B, et al. Association between respiratory syncytial virus hospitalization in infancy and childhood asthma. Pediatr Pulmonol. 2020 May;55(5):1104-10. doi: 10.1002/ppul.24676.

82. Papi A, Ison MG, Langley JM, Lee DG, Leroux-Roels I, Martinon-Torres F, et al. ; AReSVi-006 Study Group. Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults. N Engl J Med. 2023 Feb 16;388(7):595-608. doi: 10.1056/NEJMoa2209604.

83. Feldman RG, Antonelli-Incalzi R, Steenackers K, Lee DG, Papi A, Ison MG, et al. ; AReSVi-006 Study Group. Respiratory Syncytial Virus Prefusion F Protein Vaccine Is Efficacious in Older Adults With Underlying Medical Conditions. Clin Infect Dis. 2024 Jan 25;78(1):202-9. doi: 10.1093/cid/ciad471.

84. Ison MG, Papi A, Langley JM, Lee DG, Leroux-Roels I, Martinon-Torres F, et al. 1936. Efficacy of One Dose of the Respiratory Syncytial Virus (RSV) Prefusion F Protein Vaccine (RSVPreF3 OA) in Adults > 60 Years of Age Persists for 2 RSV Seasons. Open Forum Infect Dis. 2023 Nov 27;10(Suppl 2):ofad500.2467. doi: 10.1093/ofid/ofad500.2467.

85. National Library of Medicine. DailyMed. SYNAGIS- palivizumab injection, solution [Internet]. Disponível em: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3a0096c7-8139-44cdbba4-520ab05c2cb2 . Acessado em: 16/10/2024.

86. Gonzales T, Bergamasco A, Cristarella T, Goyer C, Wojdyla M, Oladapo A, et al. Effectiveness and Safety of Palivizumab for the Prevention of Serious Lower Respiratory Tract Infection Caused by Respiratory Syncytial Virus:A Systematic Review.Am J Perinatol. 2024 May;41(S 01):e1107-e1115. doi: 10.1055/a-1990-2633.

87. Griffin MP, Yuan Y, Takas T, Domachowske JB, Madhi SA, Manzoni P, et al. ; Nirsevimab Study Group. Single-Dose Nirsevimab for Prevention of RSV in Preterm Infants. N Engl J Med. 2020 Jul 30;383(5):415-25. doi: 10.1056/NEJMoa1913556.

88. Sun M, Lai H, Na F, Li S, Qiu X, Tian J, et al. Monoclonal Antibody for the Prevention of Respiratory Syncytial Virus in Infants and Children: A Systematic Review and Network Meta-analysis. JAMA Netw Open. 2023 Feb 1;6(2):e230023. doi: 10.1001/ jamanetworkopen.2023.0023.

89. Hammitt LL, Dagan R, Yuan Y, Baca Cots M, Bosheva M, Madhi SA, et al. ; MELODY Study Group. Nirsevimab for Prevention of RSV in Healthy Late-Preterm and Term Infants. N Engl J Med. 2022 Mar 3;386(9):837-46. doi: 10.1056/NEJMoa2110275.

90. Scelfo C, Menzella F, Fontana M, Ghidoni G, Galeone C, Facciolongo NC. Pneumonia and invasive pneumococcal diseases: the role of pneumococcal conjugate vaccine in the era of multi-drug resistance. Vaccines. 2021;9(5):420. doi:10.3390/ vaccines9050420.

91. O'Brien KL, Wolfson LJ, Watt JP, Henkle E, Deloria-Knoll M, McCall N, et al. ; Hib and Pneumococcal Global Burden of Disease Study Team.Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years:global estimates.Lancet.2009 Sep 12;374(9693):893-902. doi: 10.1016/S0140-6736(09)61204-6.

92. Song JY, Nahm MH, Moseley MA. Clinical implications of pneumococcal serotypes: invasive disease potential, clinical presentations, and antibiotic resistance. J Korean Med Sci. 2013;28(1):4-15. doi:10.3346/jkms.2013.28.1.4.

93. Li L, Cheng Y, Tu X, Yang J, Wang C, Zhang M, et al. Association between asthma and invasive pneumococcal disease risk: a systematic review and meta-analysis.Allergy Asthma Clin Immunol. 2020 Nov 10;16(1):94. doi: 10.1186/s13223-020-00492-4.

94. Castro-Rodriguez JA, Abarca K, Forno E. Asthma and the risk of invasive pneumococcal disease: a meta-analysis. Pediatrics. 2020;145(1):e20191200. doi:10.1542/peds.2019-1200.

95. Czaicki N, Bigaj J, Zielonka TM. Pneumococcal vaccine in adult asthma patients. Adv Exp Med Biol. 2021;1289:55-62. doi:10.1007/5584_2020_562.

96. CDC, Pneumococcal disease. Summary of risk-based pneumococcal vaccination recommendations [Internet]. Disponível em: https://www.cdc.gov/pneumococcal/hcp/vaccine-recommendations/risk-indications.html. Acessado em: 27/08/2024.

97. Moberley S, Holden J, Tatham DP, Andrews RM. Vaccines for preventing pneumococcal infection in adults.Cochrane Database Syst Rev. 2013;2013(1):CD000422. doi:10.1002/14651858. CD000422.pub3.

98. Gladstone RA, Jefferies JM, Tocheva AS, Beard KR, Garley D, Chong WW, et al. Five winters of pneumococcal serotype replacement in UK carriage following PCV introduction. Vaccine. 2015 Apr 21;33(17):2015-21. doi: 10.1016/j. vaccine.2015.03.012.

99. Torres A, Blasi F, Dartois N, Akova M. Which individuals are at increased risk of pneumococcal disease and why? Impact of COPD, asthma, smoking, diabetes, and/or chronic heart disease on community-acquired pneumonia and invasive pneumococcal disease.Thorax.2015;70(10):984-9.doi:10.1136/thoraxjnl-2015206780

100. Costa VC, Barreto MP, Andrade MCC, Lopes SMS, Nascimento MML, Carvalho FP, et al. Asma como fator de risco para infecção por COVID-19 em crianças:uma revisão integrativa.Enferm Bras. 2023;22(4):492-506. doi: 10.33233/eb.v22i4.5284.

101. Shi T, Pan J, Katikireddi SV, McCowan C, Kerr S, Agrawal U, et al. ; Public Health Scotland and the EAVE II Collaborators. Risk of COVID-19 hospital admission among children aged 5-17 years with asthma in Scotland: a national incident cohort study. Lancet Respir Med. 2022 Feb;10(2):191-8. doi: 10.1016/S22132600(21)00491-4.

102. Williamson EJ, Walker AJ, Bhaskaran K, Bacon S, Bates C, Morton CE, et al. Factors associated with COVID-19-related death using OpenSAFELY. Nature. 2020 Aug;584(7821):430-6. doi: 10.1038/ s41586-020-2521-4.

103. Bloom CI, Drake TM, Docherty AB, Lipworth BJ, Johnston SL, Nguyen-Van-Tam JS, et al. ; ISARIC investigators. Risk of adverse outcomes in patients with underlying respiratory conditions admitted to hospital with COVID-19: a national, multicentre prospective cohort study using the ISARIC WHO Clinical Characterization Protocol UK. Lancet Respir Med. 2021 Jul;9(7):699-711. doi: 10.1016/S2213-2600(21)00013-8.

104. Brasil, Ministério da Saúde.Esquema vacinal Covid-19 [Internet]. Disponível em:https://www.gov.br/saude/pt-br/assuntos/covid-19/esquemas-vacinais/esquema-vacinal-covid-19/view. Acessado em: 27/08/2024.

105. Caubet JC, Rudzeviciene O, Gomes E, Terreehorst I, Brockow K, Eigenmann PA.Managing a child with possible allergy to vaccine. Pediatr Allergy Immunol Off Publ Eur Soc Pediatr Allergy Immunol. 2014;25(4):394-403. doi:10.1111/pai.12132.

106. Wood RA, Berger M, Dreskin SC, Setse R, Engler RJ, Dekker CL, et al. ;Hypersensitivity Working Group of the Clinical Immunization Safety Assessment (CISA) Network.An algorithm for treatment of patients with hypersensitivity reactions after vaccines. Pediatrics. 2008 Sep;122(3):e771-7. doi: 10.1542/peds.2008-1002.

107. Brasil, Ministério da Saúde.Manual de Vigilância Epidemiológica de Eventos Adversos Pós-Vacinação [Internet].Disponível em:https://www.gov.br/saude/pt-br/centrais-de-conteudo/publicacoes/svsa/vacinacao-imunizacao-pni/manual_eventos-_adversos_pos_vacinacao_4ed_atualizada.pdf/view. Acessado em: 16/10/2024.


Submitted date:
12/15/2024

Accepted date:
12/24/2024

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