Alergia IgE mediada ao leite de vaca no adulto –
fenótipo raro

Sónia Pereira Garcia; Duarte Rodrigues Silva; Isabel Rezende

doi:10.5935/2526-5393.20230091

Comunicação Clínica e Experimental

Alergia IgE mediada ao leite de vaca no adulto – fenótipo raro

Adult IgE-mediated cow's milk allergy - a rare phenotype

Sónia Pereira Garcia; Duarte Rodrigues Silva; Isabel Rezende

http://dx.doi.org/10.5935/2526-5393.20230091 Arq Asma Alerg Imunol, vol.8, n2, p.166-168, 2024

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Resumo

A alergia às proteínas do leite de vaca é a alergia alimentar mais frequente em crianças, mas, na idade adulta, é rara, com uma prevalência estimada de 0,49-0,6%. Estudos prévios demonstraram que a tolerância espontânea na idade adulta raramente ocorre e que, durante o seguimento, a prova de provocação oral duplamente cega controlada com placebo deve ser usada para avaliação de aquisição da tolerância. Os autores apresentam um caso clínico de uma doente adulta com alergia às proteínas do leite de vaca, sensibilizada à caseína.

Palavras-chave

Hipersensibilidade ao leite, alergia ao leite de vaca, IgE, caseína, adulto.

Abstract

Cow’s milk protein allergy is the most common food allergy in children, but it is rare in adults, with an estimated prevalence of 0.49%-0.60%. Previous studies have shown that spontaneous tolerance rarely occurs in adults and that, during follow-up, the double-blind, placebo-controlled oral food challenge should be used to assess tolerance acquisition. We report the case of an adult patient with cow’s milk protein allergy, sensitized to casein.

Keywords

Milk hypersensitivity, cow’s milk allergy, IgE, casein, adult.

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Submetido em:
19/05/2024

Aceito em:
10/07/2024